Medical Condition

Chronic Myeloid Leukemia

Chronic Myeloid Leukemia (CML) is a type of cancer that affects the blood and bone marrow, the soft, spongy tissue inside your bones where all blood cells are made. In CML, your bone marrow produces too many immature white blood cells, specifically a type called myeloid cells. Unlike acute leukemias, CML is chronic, meaning it typically progresses slowly over months to years if not treated, allowing time for diagnosis and management.

Common Symptoms

  • Fatigue (feeling very tired)
  • Unexplained weight loss
  • Fever
  • Night sweats
  • Feeling full easily after eating small amounts
  • Pain or discomfort under the left ribs (due to an enlarged spleen)
  • Bone or joint pain
  • Pale skin
  • Shortness of breath

Clinical Sources

Diagnostic Lab Tests

Tests commonly used to diagnose or monitor Chronic Myeloid Leukemia:

Basophils (DC)

Basophils are the least common type of white blood cell, involved in allergic responses an...

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Basophils (Absolute)

Basophils are the least common leukocyte in a Complete Blood Picture. They contain granule...

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Basophils

Component of White Blood Cell differential....

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Basophils

Basophils are the least common type of white blood cell. They play a key role in the immun...

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BCR/ABL Quantification

The BCR-ABL1 quantification test uses Real-Time Quantitative PCR (RQ-PCR) to measure the a...

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Basophils

Basophils are a type of white blood cell (leukocyte) that plays a critical role in the imm...

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BCR-ABL1 Translocation [t(9;22)]

The BCR-ABL1 fusion gene, resulting from the translocation between chromosomes 9 and 22 (t...

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BCR-ABL Gene Rearrangement

The BCR-ABL test detects a specific genetic abnormality known as the Philadelphia chromoso...

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Medically Reviewed by Dr. Binoy Babu, MBBS

Board Certified Doctor • 10+ Years Clinical Experience

Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.

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