Leprosy (Hansen's Disease)
Leprosy, also known as Hansen's Disease, is a chronic infectious disease caused by a specific type of slow-growing bacteria called *Mycobacterium leprae*. It primarily affects the skin, nerves outside the brain and spinal cord (peripheral nerves), the upper respiratory tract, eyes, and testes. It's important to understand that leprosy is completely curable with multi-drug therapy, and it is not highly contagious. Most people have a natural immunity to the bacteria, meaning they won't develop the disease even if exposed. The disease is transmitted through prolonged, close contact with an untreated person who has leprosy, typically via respiratory droplets from the nose and mouth during coughing or sneezing. However, it is not easily spread, and casual contact (like shaking hands or sitting next to someone) does not transmit the disease. The incubation period (the time between exposure and symptom onset) can be very long, ranging from a few months to 20 years or more. Lab tests are crucial for diagnosing leprosy, determining its specific type (such as paucibacillary or multibacillary, which guides treatment), and monitoring the effectiveness of therapy. These tests often involve examining tissue samples (biopsies) from affected skin or nerves, or looking for the bacteria in smears from skin lesions. Confirming the diagnosis through these tests allows your healthcare team to start the appropriate multi-drug treatment, which is highly effective in curing the disease and preventing further complications.
Common Symptoms
- Skin patches (discolored, raised, or flat) that may be numb or have decreased sensation
- Numbness or loss of feeling, especially in the hands, feet, arms, and legs
- Muscle weakness or paralysis, particularly in the hands and feet
- Thickened nerves, often visible or palpable under the skin (e.g., elbow, wrist, knee)
- Eye problems, such as dryness, reduced blinking, or vision changes
Clinical Sources
- What Is Leprosy (Hansen’s Disease)?Cleveland Clinic
- Leprosy: MedlinePlus Medical EncyclopediaMedlinePlus
- Leprosy: MedlinePlus GeneticsMedlinePlus
Diagnostic Lab Tests
Tests commonly used to diagnose or monitor Leprosy (Hansen's Disease):
Ear Clipping For AFB
The Ear Clipping for AFB (Acid-Fast Bacilli) test, also known as a Slit-Skin Smear (SSS), ...
Slit Skin Smear (2 Site)
The Slit Skin Smear (SSS) is a microscopic examination used to detect Acid-Fast Bacilli (A...
Skin Clip For A.F.B. (Acid-Fast Bacilli)
An Acid-Fast Bacilli (AFB) skin clip or slit-skin smear is a specialized microbiological t...
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