Multicentric Castleman Disease
Multicentric Castleman Disease (MCD) is a rare disorder that involves an overgrowth of immune cells, primarily in your lymph nodes. Unlike the more localized Unicentric Castleman Disease, 'multicentric' means it affects multiple lymph nodes and often other organs throughout your body. While it's not a cancer, MCD can cause a wide range of symptoms due to an overactive immune system and excessive inflammation. It's a complex condition that can impact various body systems, and understanding your specific type is crucial for treatment.
Common Symptoms
- Swollen lymph nodes (often in the neck, armpits, or groin)
- Fever
- Night sweats
- Unexplained weight loss
- Fatigue or weakness
- Enlarged liver or spleen
- Anemia (low red blood cell count)
- Skin rash
- Fluid retention (edema)
Clinical Sources
- Castleman Disease: Types, Symptoms & TreatmentCleveland Clinic
Diagnostic Lab Tests
Tests commonly used to diagnose or monitor Multicentric Castleman Disease:
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