Absolute Eosinophil Count
- Sample Type
- Whole Blood
- Fasting
- No
- Unit
- cells/µL
Function
Eosinophils are a specialized type of white blood cell (leukocyte) that play a dual role in the immune system. They are primarily responsible for combating multicellular parasites and certain infections in vertebrates. Additionally, they are key mediators of allergic reactions and asthma pathogenesis, releasing granules containing enzymes that can destroy pathogens but also cause tissue damage.
Why it is Ordered
An Absolute Eosinophil Count (AEC) is ordered to investigate allergic disorders, skin diseases (like dermatitis), or suspected parasitic infections. It is also used to monitor the severity of eosinophilic esophagitis or hypereosinophilic syndrome and to assess the response to certain medications like corticosteroids.
Associated Conditions
Abnormal AEC levels are linked to:
- Allergies and Asthma: Common causes of moderate elevation.
- Parasitic Infections: Helminth (worm) infestations often trigger high counts.
- Autoimmune Diseases: Such as Churg-Strauss syndrome.
- Certain Cancers: Including Hodgkin's lymphoma and some leukemias.
- Adrenal Insufficiency: Which can lead to unexpectedly high eosinophil levels.
Check Your Result
Check Your Result
Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
Eosinophil counts fluctuate throughout the day (diurnal variation), typically being lowest in the morning and highest at night. Stress, recent steroid use, or even the timing of the blood draw can significantly alter results. A second opinion is recommended if a high count is found in an asymptomatic patient to rule out transient causes like seasonal allergies.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Absolute Eosinophil Count:
Official Sources
- EAACI guidelines on the management of IgE-mediated food allergy - PubMedpubmed.ncbi.nlm.nih.gov
Research & Guidelines
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
Get Notified When Dr. Babu Is Available