Adenosine Deaminase (ADA), Ascitic Fluid
- Sample Type
- Standard
- Fasting
- No
- Unit
- U/L
Adenosine Deaminase (ADA) is an enzyme involved in purine metabolism, primarily produced by T-lymphocytes. In the context of ascitic fluid analysis, it is a highly sensitive and specific biomarker for Tuberculous Peritonitis. Elevated levels indicate a cellular immune response triggered by Mycobacterium tuberculosis. While the Gold Standard for diagnosis remains a peritoneal biopsy or culture, ADA provides a rapid, non-invasive surrogate to differentiate TB from other causes of ascites like cirrhosis or portal hypertension.
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Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
ADA levels can be falsely elevated in cases of peritoneal carcinomatosis, lymphoma, or certain collagen vascular diseases (like SLE), potentially leading to a misdiagnosis of tuberculosis. Conversely, in immunocompromised patients, the response might be blunted.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Adenosine Deaminase (ADA), Ascitic Fluid:
Official Sources
- Tuberculous Peritonitis - PMCpmc.ncbi.nlm.nih.gov
Research & Guidelines
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Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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