Alpha-1 Globulin
- Sample Type
- Standard
- Fasting
- No
- Unit
- g/dL
Alpha-1 globulin is a fraction of serum proteins identified during electrophoresis. Over 90% of this fraction consists of Alpha-1 Antitrypsin (A1AT), a protease inhibitor that protects tissues (especially the lungs) from enzymes like neutrophil elastase. It is also an 'acute-phase reactant,' meaning its levels rise during systemic inflammation. Measuring this fraction helps screen for genetic A1AT deficiency or monitor inflammatory states.
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Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
Since it is an acute-phase reactant, a 'normal' Alpha-1 globulin level might actually be a 'low' level masked by concurrent inflammation. Genetic testing (phenotyping/genotyping) is often required if a deficiency is suspected clinically, regardless of the electrophoresis result.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Alpha-1 Globulin:
Official Sources
- Globulin Test: MedlinePlus Medical TestMedlinePlus
Research & Guidelines
- PubMed: Alpha-1 Globulin Clinical GuidelinesNCBI / PubMed
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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