Hematology

Alpha-2 Globulin

Normal Range
0.6 - 1.0 g/dL
Sample Type
Standard
Fasting
No
Unit
g/dL

The Alpha-2 globulin fraction consists primarily of Alpha-2 Macroglobulin and Haptoglobin. In Serum Electrophoresis, this band is particularly useful for identifying acute phase responses and protein-losing enteropathies or nephropathies. Because Alpha-2 macroglobulin is a large molecule, it is often retained and even upregulated in conditions where smaller proteins like albumin are lost.

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Interactive
g/dL

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Why Context Matters

Isolated elevations may be due to estrogen therapy or oral contraceptives rather than inflammation; conversely, hemolysis within the blood sample can consume haptoglobin and artificially lower this fraction.

Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.

Clinical References

Source-of-truth databases and clinical guidelines for Alpha-2 Globulin:

Research & Guidelines

Related Indicators

Activated Partial Thromboplastin Time (APTT)

View Range

Blood Cell Morphology

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AML Comboquest 9

View Range
DR

Medically Reviewed by Dr. Binoy Babu, MBBS

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Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.

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