ImmunologyInfectious Disease

Anti HBs Titres

Normal Range
> 10 mIU/mL (Immune)
Sample Type
Serum
Fasting
No
Unit
mIU/mL

Function

The Anti-HBs (Hepatitis B Surface Antibody) test detects the presence and concentration of antibodies against the Hepatitis B surface antigen. The presence of these antibodies indicates that the person has developed immunity to the Hepatitis B virus (HBV).

Why it is Ordered

This test is primarily used to determine if a person is protected against HBV. It is ordered after a full course of the Hepatitis B vaccine to confirm 'seroconversion' (successful vaccination). It is also used in 'Hepatitis Panels' to determine if a person has recovered from a past acute infection, as opposed to being a chronic carrier.

Associated Conditions

  • Post-Vaccination Immunity: A titre >10 mIU/mL is the international standard for protection.
  • Recovery from Infection: If Anti-HBs is positive along with Anti-HBc (Core antibody), it indicates natural immunity from a resolved infection.
  • Non-responder Status: Some individuals do not develop antibodies even after multiple vaccine series.
  • Chronic Hepatitis B: In chronic cases, the surface antibody is usually absent while the surface antigen (HBsAg) remains present.

Clinical Utility

Healthcare workers are routinely screened for these titres to ensure workplace safety. If titres drop below 10 mIU/mL over several years, a booster dose may be recommended, although 'immunological memory' often persists even when titres are low.

Check Your Result

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Interactive
mIU/mL

Enter your lab result to see where you stand compared to the standard reference range.

Why Context Matters

Titres can wane over time, leading to a 'negative' result even if the person is still biologically protected due to memory T-cells. Recent blood transfusions or administration of immunoglobulin can cause a temporary false-positive for immunity. A second opinion can help differentiate between 'vaccine-induced immunity' and 'natural immunity' by looking at other markers like the Core Antibody.

Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.

Clinical References

Source-of-truth databases and clinical guidelines for Anti HBs Titres:

Research & Guidelines

Related Indicators

A.S.O. Titre

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Allergy Profile (Veg, Non-Veg, Inhalants) + Total IgE

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Allergy Profile Without Drugs

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DR

Medically Reviewed by Dr. Binoy Babu, MBBS

Board Certified Doctor • 10+ Years Clinical Experience

Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.

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