Respiratory

Bicarbonate (HCO3)

Normal Range
22 - 28 mEq/L
Sample Type
Standard
Fasting
No
Unit
mEq/L

Bicarbonate is a vital byproduct of the body's metabolism and acts as a buffer to maintain the blood's pH. In an Arterial Blood Gas (ABG) analysis, the HCO3 level represents the metabolic component of acid-base balance. It helps clinicians determine if a patient has metabolic acidosis or alkalosis and whether the kidneys are effectively compensating for respiratory disturbances.

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mEq/L

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Why Context Matters

Bicarbonate levels calculated in an ABG (using the Henderson-Hasselbalch equation) may differ slightly from 'Total CO2' measured in a venous metabolic panel. Chronic use of diuretics or laxatives and chronic obstructive pulmonary disease (COPD) can cause compensatory shifts that don't represent a primary metabolic disorder.

Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.

Clinical References

Source-of-truth databases and clinical guidelines for Bicarbonate (HCO3):

Related Indicators

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Medically Reviewed by Dr. Binoy Babu, MBBS

Board Certified Doctor • 10+ Years Clinical Experience

Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.

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