Bicarbonate (HCO3)
- Sample Type
- Standard
- Fasting
- No
- Unit
- mEq/L
Bicarbonate is a vital byproduct of the body's metabolism and acts as a buffer to maintain the blood's pH. In an Arterial Blood Gas (ABG) analysis, the HCO3 level represents the metabolic component of acid-base balance. It helps clinicians determine if a patient has metabolic acidosis or alkalosis and whether the kidneys are effectively compensating for respiratory disturbances.
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Why Context Matters
Bicarbonate levels calculated in an ABG (using the Henderson-Hasselbalch equation) may differ slightly from 'Total CO2' measured in a venous metabolic panel. Chronic use of diuretics or laxatives and chronic obstructive pulmonary disease (COPD) can cause compensatory shifts that don't represent a primary metabolic disorder.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Bicarbonate (HCO3):
Official Sources
- Bicarbonate (Total CO2) Test - Testing.comTesting.com
Research & Guidelines
- PubMed: Bicarbonate (HCO3) Clinical GuidelinesNCBI / PubMed
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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