Eosinophils
- Sample Type
- Standard
- Fasting
- No
- Unit
- %
Eosinophils are a type of white blood cell usually involved in allergic reactions and parasitic infections. In a CSF Differential Count, their presence is highly abnormal (eosinophilic pleocytosis). Normally, there are zero eosinophils in the cerebrospinal fluid. Their detection indicates a specific inflammatory response within the central nervous system, often helping to distinguish between common bacterial meningitis and rarer causes.
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Why Context Matters
The presence of eosinophils in CSF can be caused by mechanical factors like a ventriculoperitoneal (VP) shunt. A 'high' count in the CSF does not always mean an active infection; it can be a hypersensitivity reaction to hardware or a reaction to certain medications administered intrathecally.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Eosinophils:
Official Sources
- Eosinophilia - Mayo ClinicMayo Clinic
Research & Guidelines
- PubMed: Eosinophils Clinical GuidelinesNCBI / PubMed
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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