PathologyOncology

F.N.A.C Procedure

Normal Range
Negative for Malignancy
Sample Type
Tissue Aspirate
Fasting
No
Unit
N/A

Function

Fine Needle Aspiration Cytology (FNAC) is a rapid, minimally invasive diagnostic procedure used to investigate lumps or masses located just under the skin (e.g., in the thyroid, breast, or lymph nodes). The primary function is to determine whether a lesion is inflammatory, benign, or malignant by extracting a small sample of cells using a thin, hollow needle.

Why it is Ordered

Physicians order an FNAC when a patient presents with a palpable nodule or an abnormality detected during imaging (like an ultrasound or CT scan). It is the first-line investigation for:

  • Thyroid Nodules: To distinguish between benign goiter and thyroid cancer.
  • Breast Lumps: To evaluate suspicious masses found during a mammogram.
  • Lymphadenopathy: To check for lymphoma or metastatic spread from other organs.
  • Salivary Gland Masses: To evaluate swellings in the parotid or submandibular glands.

Associated Conditions

Results from an FNAC can lead to the diagnosis of various conditions, including:

  • Malignancy: Carcinomas, lymphomas, and sarcomas.
  • Benign Tumors: Fibroadenomas or lipomas.
  • Infections: Tuberculosis (characterized by granulomatous inflammation) or abscesses.
  • Cysts: Simple fluid-filled sacs that resolve upon aspiration.

FNAC is highly valued for its high sensitivity and specificity, often sparing patients from more invasive surgical biopsies if the result is clearly benign or diagnostic of a specific condition.

Check Your Result

Check Your Result

Interactive
N/A

Enter your lab result to see where you stand compared to the standard reference range.

Why Context Matters

FNAC results are highly dependent on the skill of the person performing the aspiration (to ensure a cellular sample) and the cytopathologist interpreting the slides. 'Inadequate' or 'Acellular' samples can lead to false negatives. Furthermore, certain tumors (like follicular thyroid neoplasms) cannot be definitively classified as benign or malignant by FNAC alone, necessitating a second opinion or surgical excision for histology.

Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.

Clinical References

Source-of-truth databases and clinical guidelines for F.N.A.C Procedure:

Related Indicators

DR

Medically Reviewed by Dr. Binoy Babu, MBBS

Board Certified Doctor • 10+ Years Clinical Experience

Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.

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