F.N.A.C Procedure
- Sample Type
- Tissue Aspirate
- Fasting
- No
- Unit
- N/A
Function
Fine Needle Aspiration Cytology (FNAC) is a rapid, minimally invasive diagnostic procedure used to investigate lumps or masses located just under the skin (e.g., in the thyroid, breast, or lymph nodes). The primary function is to determine whether a lesion is inflammatory, benign, or malignant by extracting a small sample of cells using a thin, hollow needle.
Why it is Ordered
Physicians order an FNAC when a patient presents with a palpable nodule or an abnormality detected during imaging (like an ultrasound or CT scan). It is the first-line investigation for:
- Thyroid Nodules: To distinguish between benign goiter and thyroid cancer.
- Breast Lumps: To evaluate suspicious masses found during a mammogram.
- Lymphadenopathy: To check for lymphoma or metastatic spread from other organs.
- Salivary Gland Masses: To evaluate swellings in the parotid or submandibular glands.
Associated Conditions
Results from an FNAC can lead to the diagnosis of various conditions, including:
- Malignancy: Carcinomas, lymphomas, and sarcomas.
- Benign Tumors: Fibroadenomas or lipomas.
- Infections: Tuberculosis (characterized by granulomatous inflammation) or abscesses.
- Cysts: Simple fluid-filled sacs that resolve upon aspiration.
FNAC is highly valued for its high sensitivity and specificity, often sparing patients from more invasive surgical biopsies if the result is clearly benign or diagnostic of a specific condition.
Check Your Result
Check Your Result
Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
FNAC results are highly dependent on the skill of the person performing the aspiration (to ensure a cellular sample) and the cytopathologist interpreting the slides. 'Inadequate' or 'Acellular' samples can lead to false negatives. Furthermore, certain tumors (like follicular thyroid neoplasms) cannot be definitively classified as benign or malignant by FNAC alone, necessitating a second opinion or surgical excision for histology.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for F.N.A.C Procedure:
Official Sources
- Breast Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology - PubMedpubmed.ncbi.nlm.nih.gov
- Gastric Cancer, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology - PubMedpubmed.ncbi.nlm.nih.gov
- Colon Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology - PubMedpubmed.ncbi.nlm.nih.gov
Research & Guidelines
- PubMed: F.N.A.C Procedure Clinical GuidelinesNCBI / PubMed
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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