High-Density Lipoprotein (HDL) Cholesterol
- Sample Type
- Standard
- Fasting
- No
- Unit
- mg/dL
HDL cholesterol is often referred to as 'good' cholesterol because it facilitates reverse cholesterol transport, carrying excess cholesterol from the peripheral tissues and arterial walls back to the liver for excretion. Within a Lipid Profile, HDL is a major negative risk factor for coronary artery disease (CAD). Higher levels are associated with lower cardiovascular risk, while low levels are a component of metabolic syndrome and are predictive of atherosclerosis, even when LDL levels are within a normal range.
Check Your Result
Check Your Result
Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
Low HDL can be influenced by transient factors like acute illness, smoking, or specific medications (e.g., anabolic steroids, beta-blockers). Conversely, very high HDL (cardioprotective) may sometimes be dysfunctional in rare genetic conditions, failing to provide the expected protection against heart disease.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for High-Density Lipoprotein (HDL) Cholesterol:
Official Sources
- 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes-2025 - PubMedpubmed.ncbi.nlm.nih.gov
Research & Guidelines
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
Get Notified When Dr. Babu Is Available