Pus Cells (Leukocytes) in Stool
- Sample Type
- Standard
- Fasting
- No
- Unit
- /hpf
The presence of Pus Cells (Leukocytes) in a stool sample is a significant indicator of intestinal wall inflammation. In a healthy digestive tract, white blood cells are typically absent or present in very low numbers. When found in significant quantities, it suggests that the immune system is responding to an insult in the gastrointestinal tract, most commonly caused by invasive bacterial infections (like Shigella, Salmonella, or Campylobacter) rather than viral pathogens. It is also a key marker in monitoring Inflammatory Bowel Disease (IBD) such as Ulcerative Colitis or Crohn’s Disease during flare-ups.
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Why Context Matters
Pus cells can degrade rapidly if the stool sample is not processed quickly, potentially leading to a false-negative result. Conversely, the presence of pus cells does not distinguish between an acute infection and a chronic inflammatory condition, requiring clinical correlation.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Pus Cells (Leukocytes) in Stool:
Official Sources
- ACG Clinical Guideline Update: Ulcerative Colitis in Adults - PubMedpubmed.ncbi.nlm.nih.gov
Research & Guidelines
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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