Total Bilirubin
- Sample Type
- Serum
- Fasting
- Required
- Unit
- mg/dL
Function
Bilirubin is a yellowish pigment formed during the normal breakdown of red blood cells (hemolysis). Total Bilirubin measures the combination of 'unconjugated' (indirect) bilirubin, which travels in the blood to the liver, and 'conjugated' (direct) bilirubin, which has been processed by the liver for excretion into the bile.
Why it is Ordered
This test is a staple of Liver Function Tests (LFTs). It is used to diagnose and monitor liver diseases such as hepatitis or cirrhosis, evaluate potential bile duct obstructions (gallstones), and investigate the cause of jaundice (yellowing of the skin and eyes). It is also used to monitor newborns for neonatal jaundice.
Associated Conditions
- Hepatitis: Viral or toxic inflammation of the liver.
- Gilbert's Syndrome: A common, harmless genetic condition where the liver processes bilirubin slowly.
- Hemolytic Anemia: Conditions causing rapid destruction of red blood cells.
- Choledocholithiasis: Gallstones blocking the bile duct.
Check Your Result
Check Your Result
Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
Prolonged fasting or strenuous exercise can cause a transient rise in bilirubin, particularly in those with Gilbert's Syndrome. Conversely, exposure of the blood sample to strong light can degrade bilirubin, leading to falsely low results. High levels of Vitamin C or certain antibiotics can also interfere with the chemical assay.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Total Bilirubin:
Official Sources
- Bilirubin test - Mayo ClinicMayo Clinic
Research & Guidelines
- PubMed: Total Bilirubin Clinical GuidelinesNCBI / PubMed
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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