Total Iron Binding Capacity (TIBC)
- Sample Type
- Standard
- Fasting
- No
- Unit
- µg/dL
TIBC is a functional measure of the maximum amount of iron that can be bound by serum proteins, primarily transferrin. In an Iron Deficiency Profile, TIBC is used alongside serum iron and ferritin to calculate Transferrin Saturation. It is a critical diagnostic tool: in iron deficiency, the body increases transferrin production to 'scavenge' for iron, leading to an elevated TIBC. This helps differentiate iron deficiency anemia from the anemia of chronic disease.
Check Your Result
Check Your Result
Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
TIBC levels are affected by liver function (where transferrin is produced) and systemic inflammation. Serum TIBC may be falsely low in patients with malnutrition or nephrotic syndrome (protein loss), even if they are iron deficient, potentially masking the diagnosis.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Total Iron Binding Capacity (TIBC):
Official Sources
- Iron Deficiency Anemia - Hematology.orghematology.org
Research & Guidelines
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
Get Notified When Dr. Babu Is Available