Immunology

Anti-Centromere B

Normal Range
< 1.0 Index
Sample Type
Standard
Fasting
No
Unit
Index

Anti-Centromere B antibodies target proteins associated with the centromere of chromosomes. This test is a critical component of an ANA (Antinuclear Antibody) Profile. It is highly specific for Limited Cutaneous Systemic Sclerosis, formerly known as CREST Syndrome (Calcinosis, Raynaud's, Esophageal dysmotility, Sclerodactyly, and Telangiectasia). Its presence helps differentiate limited scleroderma from diffuse systemic sclerosis and other connective tissue diseases.

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Interactive
Index

Enter your lab result to see where you stand compared to the standard reference range.

Why Context Matters

While highly specific, a positive result does not define the severity of the disease. Furthermore, low-level positives can occur in other autoimmune conditions like Primary Biliary Cholangitis (PBC) or even in healthy elderly individuals.

Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.

Clinical References

Source-of-truth databases and clinical guidelines for Anti-Centromere B:

Research & Guidelines

Related Indicators

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A.S.O. Titre

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Allergy Profile (Veg, Non-Veg, Inhalants) + Total IgE

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DR

Medically Reviewed by Dr. Binoy Babu, MBBS

Board Certified Doctor • 10+ Years Clinical Experience

Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.

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