Anti-SSA (Ro) Antibody
- Sample Type
- Standard
- Fasting
- No
- Unit
- Index
Anti-SSA (Ro) is an Extractable Nuclear Antigen (ENA) antibody commonly associated with Sjögren's Syndrome (present in 60-90% of cases) and Systemic Lupus Erythematosus (SLE). It targets the Ro60 and Ro52 ribonucleoprotein complexes. Within an ANA Profile, its detection is critical for identifying patients at risk for photosensitive skin rashes and, most importantly, for pregnant women, as these antibodies can cross the placenta and cause neonatal lupus or congenital heart block in the fetus.
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Check Your Result
Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
Some patients may be Anti-SSA positive but ANA negative on routine screening (specifically if HEp-2 substrates are used). Furthermore, the presence of these antibodies does not always correlate with disease activity, and asymptomatic individuals may test positive years before clinical symptoms appear.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Anti-SSA (Ro) Antibody:
Official Sources
Research & Guidelines
- PubMed: Anti-SSA (Ro) Antibody Clinical GuidelinesNCBI / PubMed
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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