Hemoglobin C
- Sample Type
- Standard
- Fasting
- No
- Unit
- %
Hemoglobin C is an abnormal variant of hemoglobin caused by a substitution in the beta-globin chain. Using High-Performance Liquid Chromatography (HPLC), this test quantifies the percentage of HbC. It is used to diagnose Hemoglobin C trait (HbAC) or Hemoglobin C disease (HbCC). While often milder than sickle cell disease, its identification is crucial for genetic counseling and for identifying compound heterozygous states like HbSC disease.
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Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
The presence of HbC can interfere with HbA1c measurements (used for diabetes monitoring) on certain platforms. A hematologist's interpretation is required to assess the clinical impact on red cell survival and to provide appropriate prenatal counseling.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Hemoglobin C:
Official Sources
- Hemoglobin Test: MedlinePlus Medical TestMedlinePlus
- Hemoglobin test - Mayo ClinicMayo Clinic
Research & Guidelines
- PubMed: Hemoglobin C Clinical GuidelinesNCBI / PubMed
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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