Hemoglobin E
- Sample Type
- Standard
- Fasting
- No
- Unit
- %
Hemoglobin E (HbE) is an abnormal hemoglobin variant caused by a point mutation in the beta-globin chain. Using HPLC (High-Performance Liquid Chromatography), clinicians can quantify the percentage of HbE. It is highly prevalent in Southeast Asia and parts of India. Identifying HbE is crucial for diagnosing HbE trait, HbE disease, or E-Beta Thalassemia, which can range from asymptomatic to severe hemolytic anemia.
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Check Your Result
Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
Co-inheritance of alpha-thalassemia can mask or lower the percentage of HbE on HPLC, potentially leading to misclassification of the carrier status without genetic testing.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Hemoglobin E:
Official Sources
- Hemoglobin Test: MedlinePlus Medical TestMedlinePlus
- Hemoglobin test - Mayo ClinicMayo Clinic
Research & Guidelines
- PubMed: Hemoglobin E Clinical GuidelinesNCBI / PubMed
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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