Immunology

House Dust Mite (D. pteronyssinus) Specific IgE

Normal Range
< 0.35 kU/L
Sample Type
Standard
Fasting
No
Unit
kU/L

This test measures the concentration of allergen-specific Immunoglobulin E (sIgE) antibodies directed against Dermatophagoides pteronyssinus, a major species of house dust mite. In sensitized individuals, IgE binds to mast cells; subsequent exposure triggers the release of histamine and leukotrienes. This is a primary driver for allergic rhinitis, perennial asthma, and atopic dermatitis. Levels correlate with the probability of clinical symptoms upon exposure, though they do not strictly predict the severity of an allergic reaction.

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Interactive
kU/L

Enter your lab result to see where you stand compared to the standard reference range.

Why Context Matters

Cross-reactivity is a significant confounder. The protein tropomyosin found in dust mites is also present in shellfish (shrimp/crab) and cockroaches; a patient may test positive due to this shared homology rather than a primary mite allergy. Also, total IgE levels can influence the interpretation of specific IgE.

Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.

Clinical References

Source-of-truth databases and clinical guidelines for House Dust Mite (D. pteronyssinus) Specific IgE:

Related Indicators

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Medically Reviewed by Dr. Binoy Babu, MBBS

Board Certified Doctor • 10+ Years Clinical Experience

Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.

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