ImmunologyDermatology

HSV 1 & 2 IgG

Normal Range
< 0.90 (Negative)
Sample Type
Serum
Fasting
No
Unit
index

Function

The Herpes Simplex Virus (HSV) Type 1 and 2 IgG test detects long-term antibodies against the viruses responsible for cold sores (HSV-1) and genital herpes (HSV-2). IgG antibodies typically develop within weeks to months of infection and remain for life.

Why it is Ordered

It is ordered to determine if a person has ever been infected with HSV. It is particularly useful for pregnant women, individuals with partners who have herpes, or those presenting with atypical genital or oral sores.

Associated Conditions

  • HSV-1: Primarily associated with oral herpes (cold sores) but increasingly a cause of genital herpes.
  • HSV-2: Primarily associated with genital herpes.
  • Neonatal Herpes: Risk assessment for transmission during childbirth.
  • Aseptic Meningitis: Occasionally associated with HSV-2 primary infections.

Check Your Result

Check Your Result

Interactive
index

Enter your lab result to see where you stand compared to the standard reference range.

Why Context Matters

The 'window period' is a major confounding factor; it can take up to 3-6 months for IgG levels to become detectable after initial exposure. A second opinion/test is also warranted if the 'index' value is in the 'equivocal' range (0.91-1.09), as false positives are common in low-prevalence populations.

Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.

Clinical References

Source-of-truth databases and clinical guidelines for HSV 1 & 2 IgG:

Related Indicators

DR

Medically Reviewed by Dr. Binoy Babu, MBBS

Board Certified Doctor • 10+ Years Clinical Experience

Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.

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