Prolactin (PRL)
- Sample Type
- Standard
- Fasting
- No
- Unit
- ng/mL
Prolactin is a peptide hormone produced by the anterior pituitary gland, primarily known for its role in stimulating lactation. In the context of an LH/FSH profile, Prolactin is measured to investigate hypothalamic-pituitary-gonadal axis dysfunction. High prolactin levels (hyperprolactinemia) can inhibit the secretion of Gonadotropin-Releasing Hormone (GnRH), which in turn leads to decreased LH and FSH levels, causing symptoms like infertility, irregular menstrual cycles, and erectile dysfunction.
Check Your Result
Check Your Result
Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
Prolactin is highly sensitive to external factors. Secretion is pulsatile and increases with stress, physical exercise, nipple stimulation, or even a high-protein meal. Many common medications (antipsychotics, SSRIs, H2 blockers) can also falsely elevate levels, mimicking a pituitary prolactinoma.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Prolactin (PRL):
Official Sources
- Prolactinoma Management - Endotext - NCBI Bookshelfncbi.nlm.nih.gov
Research & Guidelines
- PubMed: Prolactin (PRL) Clinical GuidelinesNCBI / PubMed
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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