Allergy Profile (Veg) + Total IgE

Function

This panel combines a Total IgE measurement with specific IgE tests for a variety of plant-based (vegetarian) foods. Total IgE is an umbrella marker of the body's allergic reactivity, while specific IgE tests (ImmunoCAP or RAST) measure the immune system's response to specific proteins found in vegetables, grains, legumes, or fruits.

Why it is Ordered

It is ordered when a patient experiences symptoms like hives, swelling, wheezing, or digestive distress after consuming certain plant-based foods. It is particularly useful for individuals following vegetarian or vegan diets who may be consuming high amounts of soy, nuts, or specific grains and are trying to identify a trigger for their symptoms.

Associated Conditions

• Food Allergy (Type I Hypersensitivity): Immediate allergic reactions.
• Oral Allergy Syndrome (OAS): Itchy mouth caused by cross-reactivity between pollen and certain raw vegetables/fruits.
• Atopic Dermatitis: Eczema that may be exacerbated by food triggers.
• Anaphylaxis: A life-threatening systemic allergic reaction.

Clinical Application

A high Total IgE suggests an 'atopic' constitution (prone to allergies), while specific IgE results indicate 'sensitization.' It is critical to note that sensitization does not always equal clinical allergy; many people have specific IgE antibodies but can eat the food without symptoms. Results must be interpreted alongside a detailed clinical history.