Liver Cytosol Type 1 (LC-1) Antibody
- Sample Type
- Standard
- Fasting
- No
- Unit
- U/mL
The LC-1 antibody is a specific serological marker for Autoimmune Hepatitis (AIH) Type 2. While Anti-LKM-1 is the primary marker for AIH Type 2, LC-1 antibodies are found in approximately 30-50% of these patients and are occasionally the only marker present. Detection of LC-1 is highly specific and is often associated with more severe, rapidly progressive liver disease, particularly in younger patients and children. Within an Autoimmune Hepatitis panel, it helps differentiate AIH from chronic viral hepatitis or drug-induced liver injury.
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Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
LC-1 titers can fluctuate with disease activity or immunosuppressive therapy. Negative results do not entirely rule out AIH, especially Type 1 which involves different antibodies (ANA/ASMA).
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Liver Cytosol Type 1 (LC-1) Antibody:
Official Sources
- Anti-LKM-1 - Testing.comTesting.com
Research & Guidelines
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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