Rheumatoid Factor (RF)
- Sample Type
- Standard
- Fasting
- No
- Unit
- IU/mL
Rheumatoid Factor (RF) is an autoantibody (most commonly IgM) directed against the Fc portion of IgG. As a core component of the Arthritis Basic Screen, it serves as a primary marker for Rheumatoid Arthritis (RA). Higher titers are associated with more aggressive disease, extra-articular manifestations (like nodules), and worse long-term joint destruction.
Check Your Result
Check Your Result
Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
RF is not highly specific. It can be elevated in healthy elderly individuals, chronic infections (like Hepatitis C, Tuberculosis, or Endocarditis), and other autoimmune diseases like Sjogren's Syndrome or SLE, necessitating clinical correlation.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Rheumatoid Factor (RF):
Official Sources
- Clinical Practice Guidelines | American College of Rheumatologyrheumatology.org
Research & Guidelines
- PubMed: Rheumatoid Factor (RF) Clinical GuidelinesNCBI / PubMed
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
Get Notified When Dr. Babu Is Available