Soluble Liver Antigen (SLA) Antibody
- Sample Type
- Standard
- Fasting
- No
- Unit
- Units
The SLA antibody is a highly specific marker for Type 1 Autoimmune Hepatitis (AIH). While only present in about 10-30% of AIH patients, its presence is nearly 100% specific for the diagnosis. It is often the only marker present in 'seronegative' AIH patients and is frequently associated with a more severe disease course and a higher likelihood of relapse after corticosteroid withdrawal.
Check Your Result
Check Your Result
Enter your lab result to see where you stand compared to the standard reference range.
Why Context Matters
Because of its low sensitivity, a negative result cannot rule out Autoimmune Hepatitis. Conversely, because it is associated with severe disease, a positive result requires aggressive clinical management which might be overkill if the diagnosis is not confirmed by liver biopsy.
Lab ranges are statistical averages, not biological laws. "Normal" for a 20-year-old male isn't normal for a 60-year-old female.
Clinical References
Source-of-truth databases and clinical guidelines for Soluble Liver Antigen (SLA) Antibody:
Official Sources
- EASL Clinical Practice Guidelines on the management of autoimmune hepatitis - PubMedpubmed.ncbi.nlm.nih.gov
- EASL Clinical Practice Guidelines: Autoimmune hepatitis - PubMedpubmed.ncbi.nlm.nih.gov
Research & Guidelines
Related Indicators
Medically Reviewed by Dr. Binoy Babu, MBBS
Board Certified Doctor • 10+ Years Clinical Experience
Dr. Babu is a practicing physician dedicated to empowering patients with clear, actionable medical information. He founded 2opi to bridge the gap between complex lab reports and patient understanding, ensuring everyone has access to a reliable second opinion.
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