Allergy Profile (Veg+Non-Veg) + Total IgE

Function

This comprehensive panel measures specific Immunoglobulin E (IgE) antibodies against a variety of vegetarian and non-vegetarian food sources, alongside the Total IgE level. IgE is the antibody responsible for Type I hypersensitivity reactions. When an individual with an allergy is exposed to a specific protein (allergen), the immune system produces IgE, which triggers mast cells to release histamine, leading to allergic symptoms.

Why it is Ordered

This profile is diagnostic for individuals suffering from unexplained symptoms that occur after eating. It is ordered to:

• Pinpoint Triggers: Distinguish between common food allergens like legumes, dairy, eggs, meats, or seafood.
• Assess Atopy: Total IgE serves as a general marker for the body's 'allergic tilt' or atopic state.
• Differentiate Intolerance: Help distinguish between a true immune-mediated food allergy and a non-immune food intolerance (like lactose intolerance).

Associated Conditions

High specific IgE levels are associated with clinical food allergies, which can manifest as urticaria (hives), angioedema (swelling), gastrointestinal distress, or life-threatening anaphylaxis. Chronically elevated Total IgE can be seen in asthma, atopic dermatitis (eczema), and allergic rhinitis. However, Total IgE can also be elevated in non-allergic conditions such as parasitic infections (helminths) or certain rare immunodeficiencies like Hyper-IgE Syndrome (Job's Syndrome).