Disseminated Intravascular Coagulation (DIC)
DIC is a rare, life-threatening condition in which proteins that control blood clotting become overactive. This leads to widespread clotting in small vessels, followed by severe bleeding due to depletion of clotting factors and platelets.
Common Symptoms
- Bleeding (from multiple sites)
- Bruising
- Petechiae
- Organ dysfunction
- Low blood pressure
Clinical Sources
- Disseminated Intravascular Coagulation (DIC): Causes & SymptomsCleveland Clinic
- D-Dimer Test: What It Is, What It Is Used For, Risks & ResultsCleveland Clinic
Diagnostic Lab Tests
Tests commonly used to diagnose or monitor Disseminated Intravascular Coagulation (DIC):
Interleukin 6
Interleukin 6 (IL-6) is a versatile pro-inflammatory cytokine produced by various cells, i...
Complete Blood Count (CBC)
The Complete Blood Count (CBC) is a fundamental diagnostic panel that measures the various...
Blood Cell Morphology
Blood Cell Morphology is a qualitative microscopic examination of a blood smear. A patholo...
D-Dimer
D-Dimer is a protein fragment (fibrin degradation product) that is made when a blood clot ...
Erythrocyte Sedimentation Rate (ESR)
ESR is a non-specific marker of systemic inflammation. It measures the rate at which red b...
D-Dimer
D-Dimer is a fibrin degradation product, a small protein fragment present in the blood aft...
Mean Platelet Volume (MPV)
MPV measures the average size of platelets in the blood. Younger platelets are generally l...
Platelet Count (PLT)
Platelets (thrombocytes) are specialized cell fragments essential for hemostasis (blood cl...
Platelet Count
Platelets (thrombocytes) are small cell fragments essential for primary hemostasis. When b...
D-Dimer
D-Dimer is a fibrin degradation product (FDP), a small protein fragment present in the blo...
Erythrocyte Sedimentation Rate
The Erythrocyte Sedimentation Rate (ESR) is a common hematology test that measures how qui...
Fibrinogen
Fibrinogen, also known as Factor I, is a glycoprotein produced by the liver that plays a c...
Platelet Count
Platelets (thrombocytes) are essential for primary hemostasis and clot formation. Within a...
Fibrinogen
Fibrinogen, also known as Factor I, is a soluble plasma glycoprotein synthesized in the li...
Complete Blood Picture
The Complete Blood Picture (CBP), also known as a Complete Blood Count (CBC), is one of th...
Partial Thromboplastin Time (PTT)
The Partial Thromboplastin Time (PTT) test measures the time it takes for a blood clot to ...
Platelet Count
Platelets (thrombocytes) are cell fragments essential for blood clotting and hemostasis. T...
Phospholipid Screen IgG, IgM
The Phospholipid Screen (specifically Cardiolipin antibodies) detects autoantibodies produ...
Activated Partial Thromboplastin Time (APTT)
The Activated Partial Thromboplastin Time (APTT) is a functional measure of the 'intrinsic...
Peripheral Smear
A Peripheral Smear (or Peripheral Blood Film) is a manual microscopic examination of a thi...
JAK-2 Mutation (Exon 14, 12)
The Janus Kinase 2 (JAK2) gene provides instructions for making a protein that promotes th...
Platelet Count
Platelets, or thrombocytes, are small cell fragments in the blood that are essential for n...
Erythrocyte Sedimentation Rate (ESR)
ESR measures the distance red blood cells fall in a tube over one hour. In an Arthritis Ba...
COVID Panel Bio Chemistry
The COVID Biochemistry Panel is a cluster of laboratory tests used to monitor the physiolo...
Mean Platelet Volume (MPV)
MPV measures the average size of platelets in the blood. Since larger platelets are typica...
Peripheral Blood Morphology
Peripheral Blood Morphology, often referred to as a peripheral blood smear, is a diagnosti...
Platelet Count (PLT)
Platelets (thrombocytes) are essential components of the Hemostatic system, responsible fo...
Bleeding Time and Clotting Time
The Bleeding Time (BT) and Clotting Time (CT) tests are fundamental screening tools used t...
Hemoglobin, Total Count, Differential Count, and Platelet Count
This panel, often referred to as a Complete Blood Count (CBC) component, evaluates the thr...
Hemoglobin, TC, DC, ESR & Platelet Count
This panel is a comprehensive hematological assessment. It includes Hemoglobin (Hb) for ox...
Erythrocyte Sedimentation Rate (ESR)
The Erythrocyte Sedimentation Rate (ESR) is a non-specific marker of systemic inflammation...
Fibrinogen
Fibrinogen is a soluble plasma glycoprotein (Factor I) that is converted to fibrin by thro...
Complete Blood Count
The Complete Blood Count (CBC) is one of the most common and essential diagnostic tests in...
Lupus Anticoagulant
The Lupus Anticoagulant (LA) test is a functional assay used to detect specific autoantibo...
Platelet Count
Platelets are essential for primary hemostasis and thrombus formation. In a COVID Panel He...
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